sphingosine相关论文
目的 探讨alphastatin对裸鼠体内新生血管形成和人胃癌细胞裸鼠移植瘤血管生成的抑制作用及机制.方法 裸鼠皮下注射基质胶溶液形成......
Aim:To characterize sphingosine methyltransferase in rat tissues.Methods:By using S-adenosyl-L-(methyl-3H) methionine,en......
Epicardial progenitor cells (EpiCs) which are derived from the proepicardium have the potential to differentiate into co......
目的观察磷酸鞘氨醇(S1P)干预对胰腺癌PANC1细胞侵袭、转移能力的影响。方法采用20、40、80、100、150、200 nmol/L S1P干预PANC1......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
1-磷酸鞘氨醇（sphingosine 1-phosphate，S1P）是鞘磷脂的一种代谢产物，广泛存在于各种类型细胞。S1P既可作为细胞外介质，又能作为细胞内......
目的 探讨鞘氨醇激酶1(SphK1)对肿瘤坏死因子α(TNF-α)诱导的气道黏蛋白(MUC)5AC的调节机制.方法 培养正常人气道上皮细胞HBE16,......
Sphingolipids are formed via the metabolism of sphingomyelin,aconstituent of the plasma membrane.or by denovosynthesis.E......
BACKGROUND:KAI1/CD82 has been reported to attenuate the process of metastases in a variety of tumors;however,its mechani......
Sphingosine kinase 1 knockout alleviates hepatic ischemia/reperfusion injury by attenuating inflamma
Background: Hepatic ischemia/reperfusion(I/R) injury remains a significant problem in clinical practice. Sphingosine kin......
目的：探讨鞘氨醇激酶1（SPHK1）和核因子（NF）-κB在非小细胞肺癌（NSCLC）组织中的表达及其与NSCLC浸润、转移和预后的关系。方法选取93例外科......
Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer
AIM:ToexaminetheexpressionofSphK1,anoncogenickinasethatproducessphingosine1-phosphate(S1P),anditscorrelationwiththeexpre......
目的探讨siRNA靶向沉默SPHK1基因对前列腺癌PC-3细胞生物学行为的影响。方法使用脂质体介导的方法转染人前列腺细胞株PC-3细胞,通......
背景与目的：碱性鞘磷脂酶（alk-SMase）是鞘磷脂（sM）新陈代谢和发挥抑制结肠癌作用的关键酶。通过体外实验探讨sM的水解产物的神经酰胺（Cer......
鞘氨醇-1-磷酸（sphingosine-1-phosphate,S1P）与细胞膜表面的G蛋白偶联受体——S1P受体（S1P receptor,S1PR）1～5结合调控下游通路,介导大......
目的探讨鞘氨醇-1-磷酸（SIP）信号通路及其抑制剂芬戈莫德（FTY720）在体外实验中对不同侵袭潜能人肝细胞癌（HCC）细胞迁移能力的作用。方法......
为探讨伏马菌素与人类食管癌发生的关系，对食管癌高发区鹤壁市郊区部分居民的伏马菌素摄入水平及尿二氢神经鞘氨醇／神经鞘氨醇（Sa/So)......
The reverse cholesterol transport mediated by highdensity lipoprotein(HDL)is an important mechanism for maintaining body......
The sphingosine kinases, SK1 and SK2, produce the potent signaling lipid sphingosine-1-phosphate (S1P). These enzymes ha......
目的建立生物样品中磷酸鞘氨醇（S1P）的定量方法。方法采用有机溶剂萃取、碱性磷酸酶脱磷酸、衍生化后经高效液相色谱仪测定动物血清......
目的探讨1-磷酸鞘氨醇（S1P）及脂联素在冠状动脉支架植入术后的预测价值。方法选择经复查冠脉造影后证实为支架内再狭窄患者50例为再......
综述了神经鞘氨醇、神经酰胺及鞘糖脂全合成研究的基本概况,重点评述了其最近的研究进展情况.......
Infiltration of myelin-specific helper T (Th) cells into the central nervous system (CNS) plays a key role in pathogenes......
Therapeutic administration of fingolimod hydrochloride (FTY720), the functional antagonist at sphingosine 1-phosphate (S......
Recent Background: Development of obesity involves promotion of preadipocyte differrentiation. This study investigated t......
Expressions of Sphingosine-1-phosphate (S1P) Receptors, Sphingosine Kinases in Malignant Bone and So
Sphingolipids are ubiquitous components of cell membranes. Their metabolites ceramide, sphingosine, and sphingosine-1-ph......
Sphingosine kinase 1 (SphK1) is an important mediator of apoptosis and the proliferation of cancer cells. It is upregula......
鞘脂类是细胞膜上普遍存存的一种成分，其代谢产物1-磷酸鞘氨醇（sphingosine-1-phosphate，SIP）既可通过胞外受体途径义可作为胞内第二信......
The sphingolipid metabolites ceramide,sphingosine,and sphingosine-1-phosphate(S1P) and its enzyme sphingosine kinase(Sph......
建立了一种检测人尿中神经鞘氨醇（Ｓｏ）和二氢神经鞘氨醇（Ｓａ）的高效液相色谱方法（ＨＰＬＣ）。离心分离尿样中的片状剥落细胞，解后用乙酯萃取、邻苯二甲衍......
Sphingosine kinase 1 dependent protein kinase C-δ activationplays an important role in acute liver f
AIM To investigate the role of protein kinase C（PKC）-δ activation in the pathogenesis of acute liverfailure （ALF） in a well......
Inhibition of sphingosine kinase 1 ameliorates acute liver failure by reducing high-mobility group b
AIM: To determine the therapeutic potential of sphingosine kinase 1(Sphk1) inhibition and its underlying mechanism in a ......
AIM: To investigate the cytoprotective effects in hepatic ischemia-reperfusion injury, we developed a new formulation of......
The importance of sphingosine kinase(SphK)and sphingosine-1-phosphate(S1P)in inflammation has been extensively demonstra......
Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid with a variety of biological activities.It is generated from t......
Sphingosine kinase-2 induced autophagy activation mediates ischemic tolenrance in primary cortical n
Aim This study is aimed to determine whether SPK2 （Sphingosine kinase-2） is involved in isoflurane preconditioning induced......
